Anne Tamar-Mattis founded Advocates for Informed Choice (AIC) (now interACT: Advocates for Intersex Youth) out of love for her intersex partner, Suegee Tamar-Mattis, after hearing the stories of intersex adults harmed because of their unique embodiment. Anne spent most of her life in service to the queer community. She served as Director of the LYRIC Lavender Center for LGBTQQ+ Youth Talkline which provided peer support for queer youth and was the first Program Director of the San Francisco LGBT Community Center. She attended UC Berkeley School of Law and started AIC to use legal tools to protect intersex young people from harm.  

David Strachan, an elder from the California intersex community who often worked with Anne, remarked about the founding of AIC:

I think that's when I got really in touch with Suegee and Anne, who I thought were really important, especially when Anne had the roundtable to start. I think her original name was Intersex Children and the Law, and then they change it to Advocates for Informed Choice. We met at an attorney's office, downtown San Francisco. There were interns, there were lawyers. I think Julie Greenberg was there; she was on the advisory committee, the medical one. So we met at a round table and sort of hashed all this stuff out. Like, where do we want to go from here kind of thing ... and then Anne created the nonprofit.